Evaluation of Drug Candidates for Preclinical Development.
Chao Han, Charles B. Davis, Binghe WangKoliko vam se sviđa ova knjiga?
Kakav je kvalitet fajla?
Preuzmite knjigu radi procene kvaliteta
Kakav je kvalitet preuzetih fajlova?
Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the "right" drug candidate for development is the key to success. In the last decade, pharmaceutical R&D departments have integrated pharmacokinetics and drug metabolism, pharmaceutics, and toxicology into early drug discovery to improve the assessment of potential drug compounds. Now, Evaluation of Drug Candidates for Preclinical Development provides a complete view and understanding of why absorption-distribution-metabolism-excretion-toxicology (ADMET) plays a pivotal role in drug discovery and development. Encompassing the three major interrelated areas in which optimization and evaluation of drug developability is most critical—pharmacokinetics and drug metabolism, pharmaceutics, and safety assessment—this unique resource encourages integrated thinking in drug discovery. The contributors to this volume Cover drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, stability, drug formulation, preclinical safety assessment, toxicology, and toxicokinetics Address developability issues that challenge pharma companies, moving beyond isolated experimental results Reveal connections between the key scien.
Kategorije:
Godina:
2010
Izdanje:
Kindle
Izdavač:
Independely Published
Jezik:
english
Strane:
306
ISBN 10:
0470044918
ISBN 13:
9780470044919
Fajl:
PDF, 1.45 MB
Vaši tagovi:
IPFS:
CID , CID Blake2b
english, 2010
Fajl će biti poslat na vaš email. Može da prođe do 1-5 minuta pre nego što ga primite.
U roku od 1-5 minuta fajl će biti dostavljen na vaš Telegram nalog.
Pažnja: Uverite se da ste povezali svoj nalog sa Telegram botom Z-Library.
U roku od 1-5 minuta fajl će biti dostavljen na vaš Kindle uređaj
Napomena: morate da verifikujete svaku knjigu koju želite da pošaljete na svoj Kindle. Proverite u svom poštanskom sandučetu verifikacioni email dopis od Amazon Kindle Support.
Konvertovanje u je u toku
Konvertovanje u nije uspešno
Premium benefits
- Send to eReaders
- Increased download limit
- File converter
- Više rezultata pretrage
- More benefits